Chlorhexidine bigluconate, which is part of the preparation, is a dichloro-containing derivative of biguanides, has a pronounced antimicrobial action, is active against vegetative forms of gram-negative and gram-positive bacteria, as well as yeasts, dermatophytes, and lipophilic viruses. It only acts on bacterial spores at elevated temperatures.
The mechanism of action of chlorhexidine involves interaction with phosphate groups on the surface of the bacterial cell, resulting in osmotic balance disruption, cell integrity disruption, and cell death. After shampooing, residual bactericidal action on the skin is maintained for up to 24 hours.
It does not have skin-resorptive action.
Application: 4% chlorhexidine antibacterial shampoo is prescribed for dogs and cats with bacterial (superfici
